The person-centered  paradigm change of Medical Science

 Antony S. Fauci, the USA “virostar”, and the USA Center of Disease Prevention, Rochelle Walensky, supporting Joe Biden’s decision to extend the vaccination anti-SARS 2 to children < 12 , based on a very weak Pfizer’s investigation, that does not control vaccines’ adverse effects over a long time, opened the USA doors to<12  pre-adolescents and  children’  vaccination influencing also European public health administrators.

They declared:

“The long-term effects that the people are apparently concerned about really have—with, I’m sure there is a very, very, very, very rare exception, but the long-term effects are really essentially non-existent in the sense of anything that has been a red flag on the part of the followup of these individuals. So, although one, I guess, can theoretically say I’m concerned about a long-term effect, the fact of the safety and the follow-up over now over a considerable period of time, obviously a year.(!!!! ) And so many individuals, we have just not seen that. So we don’t really see any true basis in that concern.” (Fauci)

“If all goes well, and we get the regulatory approval and the recommendation from the CDC, it’s entirely possible if not very likely that vaccines will be available for children from 5 to 11 within the first week or two of November”   (Fauci)

“We know how many parents are interested in getting their children between 5 and 11 vaccinated and we intend to act as quickly as we can” (Walensky)

The USA”virostar”,  and other world virostars, public health administrators, including those affected by “Donkey syndrome” in Italy and worldwide, should read with attention the following paper:

Lockhart L, Canfield J, Ezinne F et al. Nucleotide Modification Alters MicroRNA-Dependent Silencing of MicroRNA Switches. Nucleic Acids.2019;14:339-350″

Pfizer’s and Moderna’s mRNA vaccines replace uridine with N1- methyl pseudouridine to escape immunity and increase translation speed, but this substitution provokes microRNA alteration, interfering with the life survival miR silencing action. This substitution with vaccines is introduced in all the organism cells.

Adverse effects are probable (cancer-psycho-neuro-behavioral disorders) threatening over long-time children and adolescents’ health, who are not exposed to COVID-19 severity, are rarely infected, and if so, are primarily asymptomatic. Contagion risk, compared with symptomatic, is significantly reduced, as many investigations depicted.

Micro-Rna epigenetic-induced alteration by mRNA vaccines will make  very probable that the next public health problem will be the prevention of vaccine effects and treatment along with the vaccine-induced production of SARS-COV variants.  1 year is not enough to avoid concerns for life-threatening adverse effects. Leucemia could be one of these.

Concerns about  genetic adverse effects of vaccines are shared also by Luc Montagner, Medicine Nobel Prize.

A new orientation toward a person-centered health strategy is necessary primarily for children and adolescents.

Epidemiological data document that the case-fatality ratio < 29  is zero or close to zero, and inducing vaccination of children and adolescents is a crime against humanity, considering the possibility of easy and effective prevention also against other communicable and not communicable diseases through “Antiviral allostasis and preventive immunostimulation”, warranting also an immediate and natural vaccination of asymptomatic people, without adverse effects.

To date, early and effective domiciliary treatments of COVID-19 with cheap drugs already used in therapy are available, and it is possible to individuate a patient at risk of a severe clinical syndrome before the infection, allowing prevention.

Also, WHO, which suggested vaccines for > 18, (!!!!) stated:

“Children and adolescents tend to have milder disease compared to adults, so unless they are part of a group at higher risk of severe COVID-19, it is less urgent to vaccinate them than older people, those with chronic health conditions and health workers.”

The problem of mRNA induced adverse effects concerns also adults, considering the genetic and epigenetic risks which need epidemiological studies over time and worldwide and considering possibilities to prevent the infection with the antiviral allostasis and preventive immunostimulation in older people at risk of Anergy (1.2)

Moreover, we suggest to Robert Fauci and other virologists to update their fragmented and surpassed epistemologically surpassed bio-medical culture reading also these papers ( but  they do understand  the meaning of the word “epistemology”):

Federico M The conundrum of current anti-SARS-CoV-2 vaccines. Cytokine & Growth Factor Reviews.2021;60:45-61.

  Doerfler W. Adenoviral Vector DNA- and SARS-CoV-2 mRNA-Based Covid-19 Vaccines: Possible Integration into the Human Genome – Are Adenoviral Genes Expressed in Vector-based Vaccines? Virus Res. 2021 Sep;302:198466. DOI: 10.1016/j.virusres.2021.198466. Epub 2021 Jun 1. PMID: 34087261; PMCID: PMC8168329.

(Considering the DNA hybridization of vaccinated people with the chimpanzee’s DNA adenovirus by the AstraZeneca vectorial vaccine, there is the doubt that some “virostar” in the USA, in Italy, or worldwide vaccinated with Astra Zeneca could be affected by psychobiological effects of the vaccine-induced ” Chimpazee’s syndrome”. There is a simple test to be used for diagnosis: ” The banana attraction test”)  Chimpanzees do not know the meaning of the word epistemology and ethics.

We recently suggested to the USA President the change of the USA health strategy adopting the “Antiviral allostasis and preventive immunostimulation ” to avoid any risk for people otherwise damned to be persecuted by COVID-19 terrorism, health merchants, and illiterate virologists.

We suggest to those who do not know the person-centered change of medical science paradigm and the meaning of a word like “Allostasis,” the new alphabet of human physiology which revolutionized Medicine, a rapid updating.

It is necessary to understand the Person-Centered Medicine paradigm change of medical science that Fauci and other virologists and most physicians and investigators ignore.

We hope that after the recent Joe Biden’s blessing by Jorge Maria Bergoglio in the Vatican ( who also blessed vaccines as a “love act” after the signaled deaths in the USA of 14 adolescents otherwise alive), the Holy Spirit will inspire the USA President.

Giuseppe R.Brera

President of WHC and Italian Health National Committee

Director of the Ambrosiana University’s ” Scuola Medica di Milano” 


  1.  Brera G.R Sars-Cov-2 allostasis and the people and person-centered prevention. A new prevention strategy based on a people metabolic and immune shield for the pandemic shutdown. Part 1 The Sars-Cov 2 entry and COVID-19. Milan. Ambrosiana University , 2021. ISBN: 9798530093906
  1.   Brera G.R . SARS-COV 2- allostasis and the people and person-centered prevention. Part 2 The sars-cov 2- induced immunosuppression and covid-19 anergy part 3 The antiviral metabolic allostasis and preventive immunostimulation – How to induce zero risk for covid-19. Milan: Ambrosiana University: 2021 ISBN: 9798547583520




Inaugural Conference of  the 2020-2021  academic activities of Ambrosiana University



The Person-Centered Prevention Program  for pandemic prevention



Person-Centred Medicine (PCM) is the current paradigm of medical science and Medicine, and this involves the orientation of public health with a new organization of primary care and the training of doctors and students in Medicine through teachers prepared for PCM teaching. Its application, through trained doctors, allows enormous savings in suffering and costs. The PCM reconverts health to “Person-centred prevention” by promoting health education, prevention, early treatment of diseases, self-care, incentivizing individual resources, introducing and reinforcing protective factors, and buffering risk factors to improve individual resilience.
The PCM paradigm is defined as” The choice of the best possibilities for being the best human person,” which is also a political program.
In adolescence, a period of spiritual and psycho-biological formation, the PCM assumes fundamental importance throughout life because it builds an indelible trace for the future.
The Congress is held in three parts: the first is dedicated to the scientific bases of the Person-Centered Medicine interactionist and teleonomic paradigm, which will be followed by a panel dedicated to the paradigm change of Medicine. (in English) -November 13
Keynote speakers: Peter Sterling, the author of the Allostasis theory that revolutionized physiology and medical science, the fundament of the Person-Centered Medicine paradigm with other significant contributors to Medicine paradigm change .(November 13- h 15)
The second session is dedicated to adolescence. Speakers are contributors to the revolution of the paradigm of the adolescence theory. (November 13- 17,30-19,30)
The third session is dedicated to the Person-Centered Prevention paradigm, genetic and epigenetic damages induced by vaccines against SARS-COV 2, and early treatment of COVID-19.
( November 20 – h 15 in Italian-English)
Giuseppe R.Brera
Rector of the Ambrosiana University, Director of the Medical School of Milan, president of the World Health Committee and the Italian National Health Committee
Free access on zoom on registration
To give a contribution to the conference in panels (5-7′) send the enclosed abstract form to dr. Vito Galante within 7 November (1°-2° session, November 13 -3°session)





Giuseppe R.Brera

We are informed that Joe Biden, the USA President, wants to promote children and adolescents’ mRNA vaccination against SARS-COV 2.

M-RNA vaccines alter micro-RNA in any cell, and in such a way, the delicate work to silence RNA  that in the case of the epigenetic balance alteration could induce tumors and other severe pathologies. Moreover m.RNA vaccines increase the cell methylome associated with cancer. We do not know the effect of micro-RNA alterations in neurons.   Cognitive disorders, behavior alterations, and  Alzheimer’s induction could be probable. In any case, we need long-term epidemiological investigations that have been omitted by BIG-PHARMA, whose experimental trials quality has been very criticized. Micro-RNA are fundamental for health, and their alteration could be catastrophic for public health. We are underestimating the effects of epigenetic changes of mRNA vaccines on micro RNA, exposing vaccinated people to adverse effects.  A winning alternative to prevent further pandemics due to SARS-COV 2 mutation or other viruses is to promote primary and secondary prevention by inducing a natural antiviral metabolic reprogramming ( antiviral allostasis) through diet and immunostimulation  (AAVIS).  Lack of the adoption of Person-Centered change of Medicine epistemology founding the health concept intended as “The choice of the best possibilities for being the best human person,” was at the origin of the wrong strategy to cope with the pandemic’s beginning. Restrictions of human rights produced preventive effects, as Claudio Violato depicted recently, but costs for people’s mental health, work, and the economy have been high.  This strategy against human rights instituted a new health political power, like an  Orwellian culture,  but less effective than an easily accessible health education to  AAVIS, also inducing cross prevention against other communicable and non-communicable diseases like cancer.  Freedom and health are already inseparable at the experimental level, as psycho-neuro endocrine immunology depicted according to the significant contribution of Mark Laudenslager. Closing allostasis possibilities means reducing natural immunity. Freedom is the basis of a healthy allostasis,  the Sterling and Heyer’s physiology revolution forgotten by Nobel prize attribution and not yet known by almost physicians and investigators.  Allostasis is the basis of the interactionist and teleonomic person-centered revolution of the Medicine paradigm and health concept change that  WHO  omitted to formalize because of a “Donkey syndrome” pandemic. Health is relative to the interpretation quality of experience possibilities, which determines choices and lifestyle and starts from individual freedom and dignity.

Conversely, WHO and most anti-COVID 19 illiterate committees applied an outdated mechanistic conception of Medicine based on the linear causality:virus-infection –death risk while to date, the fundamental medicine paradigm is multidimensional and multifactorial based on the person-centered advances and revolution of biomedical science, primarily Allostasis, Neurobiology, Psychoneuroendocrineimmunology, Epigenetics, Affect science.  Medicine and public health must interpret any pathology as the lack of people’s health protective factors.  A public health strategy to prevent a pandemic should adopt the following multidimensional and multifactorial alphabet =  A -pathogen,  B . allostasis-C -natural immunity, D -infection risk, E disease risk, F -early therapy, G worsening risk, H death risk.  By increasing  B  and  C,  allostasis, and immunity-based people resources, we can prevent and block pandemics.  This strategy means creating a healthy lifestyle, starting from nutrition quality, education, early health care, and prevention possibilities, omitted in the SARS-COV 2 pandemic.  Without the Person-Centered  A-B-C,  the  Medicine alphabet non-known by illiterate public health officers or most virologists, any advance of biomedical science, clinical medicine, and medical education is impossible. To date, people worldwide are dependent on health merchants who want to profit from people’s diseases. They have been able to falsify scientific data like Smith&Kline in 2004, which received a penalty of 250 million dollars from the FDA. Bio-tech messianism is not the future of Medicine and public health if we want to build effective person-centered prevention.

Investigation on SARS-COV 2  depicts that there is also a limited possibility of DNA alterations.  Human DNA hybridization with heterologous  DNA  is standard with vectorial vaccines   (Astra-Seneca-Johnson). The short-term and long-term adverse effects could be hazardous because of  DNA hybridization- which is transmissible to progeny-mainly at a young age for intense immunity reactions and fatal consequences due to the closeness of corona- adenoviruses viruses infections.  (immune-complex syndrome), like occurred to a healthy girl in Italy who died after Astra-Seneca inoculation.

Moreover, what happens if the DNAs neurons of a government or public and private deans are hybridized with a chimpanzee’s DNA adenovirus or their brain is altered by mRNA vaccines. ? In Italy, healthy adolescents died because of m-RNA and Astra.Seneca vaccination-induced by government and regions’ illiterate people. We need deep and honest epidemiological investigations that BIG-PHARMA omitted. Their problem is only to sell vaccines.

 Anti-SARS-COV 2 vaccination of children and adolescents is a crime against humanity. According to epidemiology, they are not at risk of COVID-19 and asymptomatic and, if vaccinated, can be submitted to dangerous adverse effects up to death, as the USA Center for Prevention depicted. In the USA, the death of fourteen adolescents, otherwise alive, has been signaled. In the 0-29 age range, the case-fatality ratio from COVID-19 is close to zero because the young people’s natural immunity is not disturbed by cell membranes lipidic transformation as in older people, where transduction of immunity signals is altered. Inducing children and young people’s parents to authorize anti-SARS-COV vaccination is not a “Love act” as “pope” Francis written but exposes them to unuseful dangerous risks.

Moreover, the asymptomatic infection in young people promotes herd immunity like living vaccines and produces a long-lasting immunity. It is beneficial for the pandemic shutdown.  The infection ratio is half of symptomatic, and one investigation that traced 420 contacts of an asymptomatic did not find any  COVID-19.

As  President of the World Health Committee and in Italy as President of the Italian National  Health Committee, I have launched the Antiviral Allostasis and Immunostimulatory Stimulation ( AAVIS) campaign inspired by Person-Centered Medicine, the paradigm change of medical science and Medicine, which introduced the paradigm of People and Person-Centered Prevention also in the light of the formulation of the SARS-COV 2 infection relativity theory.

We started to propose AAVIS to the Russian, USA, and Romania Presidents. In Italy, we did not find an audience by a government engaged in delusional law acts introducing a people’s discrimination and control through a ” green pass” testifying a vaccination against SARS-COV 2, which does not prevent contagions but only a severe COVID-19 only in people older than 0-39.  Moreover, because of immunosenescence  in the oldest people, vaccination is effective only for a few weeks, and it requests a change of the prevention strategy toward AAVIS

Considering mRNA vaccines’ and viral vectors’ epigenetic and genetic adverse effects, respectively,  inducing a third and tomorrow more boosting is a dangerous sanitary delusion  but blessed by  BIG-PHARMA marketing plans.

Recently the Nobel Prize Luc Montagner recommended high prudence in the genetic vaccine use., confirmed by induction of genetic and epigenetic alterations.  Considering the virus’s rapid mutations like HIV, we must change preventive strategy by adopting the person-centered antiviral allostasis and immunostimulatory paradigm, which increases the freedom and responsibility-based public health, natural partner of innate immunity, superior to artificial induction of immunity from experimental vaccines with a short- time-limited immunity and adverse effects. Vaccines indeed induced a lower case/fatality ratio, but this kind of strategy, in any case, should be restricted only to people older than 29 and could induce a pandemic of adverse effects, blessed by health merchants.

SARS-COV 2  could be easily neutralizable by  AAVIS, determining a rapid and accessible shutdown of pandemic worldwide without dangerous mass vaccination and consequent adverse effects, also protecting from other pathogens and  SARS-COV 2 mutations.  AAVIS is cheap and inexpensive because founded on an effective antiviral diet and nutraceuticals. If diffused through health education could be decisive for COVID-19 and also adverse effects of vaccines prevention. AAVIS could be easily realized through media and induce cross-prevention against other communicable and non-communicable diseases like cancer.


Giuseppe R.Brera

President of the World Health Committee  and the Italian National Health Committee

Rector of the Ambrosiana University and Director of the Milan School of Medicine


Brera G.R  Medical science and health paradigm change. Milan. University Ambrosiana Editions; 2018    Internet www.

Brera G.R  Person-centered Medicine and Person-centered clinical method. Clinical results of the Medicine unitary paradigm teaching and the COVID-19 people and person-centered prevention theory. Milan. University Ambrosiana edition; 2021.   ISBN: 9798726465432

Brera G.R.  SARS-COV 2-2 allostasis and the people and person-centered prevention.

Part 1  The Sars-Cov 2 entry relativity and COVID-19. Milan.University Ambrosiana Ed. ; 2021   ISBN   9798530093906

Part 2-3  Brera G.R . SARS-COV 2- allostasis and the people and person-centered prevention. Part 2 The Sars-Cov 2- induced immunosuppression and covid-19 anergy.  Part 3 The antiviral metabolic allostasis and preventive immunostimulation  – How to induce zero risk for covid-19. Milan:  Università Ambrosiana: 2021   ISBN 9798547583520




















The “Person-centered Health relativity” and the “People and Person-Centered Prevention” theories. From epistemology to the COVID-19 pandemic shut-down.

The “Person-centered Health relativity” and the “People and Person-Centered Prevention” theories. From epistemology to the COVID-19 pandemic shut-down.


Self-Care and Well-Being in the Times of Covid-19 5 – 7 April 2021

(, promoted by the Person-Centered Medicine International College

The “Person-centered Health relativity” and the “People and Person-Centered Prevention” theories. From epistemology to the COVID-19 pandemic shut-down. [accessed Oct 04 2021].

Giuseppe R.Brera


Person-Centered Medicine (PCM) is the first extrinsic paradigm of medical science instituted due to the last forty years of advancing biomedical science and human sciences. The PCM epistemological bases are interactionism and the human nature teleonomy allowing the freedom and dignity-based “being-person” identity. The Medicine indeterministic epochal shift is similar to the discovery of quantum physics, which is allowed to constitute the “Person-centered clinical method” that integrates the obsolete one and reassesses the physician’s role as maieutic of the being person. The lecture introduces the PCM health-derived concept relativity theory and the People and Person-Centered Prevention paradigm (PPCP), whose application in the light of the SARS-COV 2 infection and complication general theory discoveries, only can shutdown the COVID-19 and other communicable and non-communicable diseases

The conundrum of current anti-SARS-CoV-2 vaccines


The conundrum of current anti-SARS-CoV-2 vaccines

Maurizio Federico


The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has given rise to the urgent need for vaccines and therapeutic interventions to address the spread of the SARS-CoV-2 virus. SARS-CoV-2 vaccines in development, and those being distributed currently, have been designed to induce neutralizing antibodies using the spike protein of the virus as an immunogen. However, the immunological correlates of protection against the virus remain unknown. This raises questions about the efficacy of current vaccination strategies. In addition, safety profiles of several vaccines seem inadequate or have not yet been evaluated under controlled experimentation. Here, evidence from the literature regarding the efforts already made to identify the immunological correlates of protection against SARS-CoV-2 infection are summarized. Furthermore, key biological features of most of the advanced vaccines and considerations regarding their safety and expected efficacy are highlighted.

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